AN INSIGHT INTO THE TREATMENT STRATEGIES OF OBESITY USING SEMAGLUTIDE AND ITS COMPETITIVE ANALOGUES: A REVIEW ARTICLE

Obesity is a major public health problem in the world. This growing rate represents an epidemic that requires immediate attention. Oral Semaglutide semaglutide compound with absorption enhancer, sodium N- (8 - [2-hydroxybenzoyl] amino) caprylate (SNAC). The mechanism of action simply produces Glucagon-like peptide-1 (GLP-1) as food-based digestive hormone acts appetite signal, stimulates insulin release, inhibits glucagon production, and regulates diarrhea. article shows correlation GLP-1 association motivation to feed Semaglutide’s anorectic effect relation cravings. We have performed complete searches from PubMed, Cochrane, Scopus, Medline, Medscape, Wiley online library 2015 2022. trial data (SUSTAIN, PIONEER, STEP) suggested decrease weight HbA 1c. SELECT showed cardiovascular safety over other anti-diabetic drugs. review summarized anti-obesity drug compared effects (oral subcutaneous) analogs.